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Brompheniraminum [INN-Latin] en es it fr

Brompheniraminum [INN-Latin] Brand names, Brompheniraminum [INN-Latin] Analogs

Brompheniraminum [INN-Latin] Brand Names Mixture

  • Drixoral Cold & Sinus (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
  • Drixoral Day/Night - Srt/Tabs (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
  • Drixoral Syrup (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
  • Drixtab Tab (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)

Brompheniraminum [INN-Latin] Chemical_Formula

C16H19BrN2

Brompheniraminum [INN-Latin] RX_link

http://www.rxlist.com/cgi/pharmclips2.cgi?keyword=%20Dexbrompheniramine

Brompheniraminum [INN-Latin] fda sheet

Brompheniraminum [INN-Latin] msds (material safety sheet)

Brompheniraminum [INN-Latin] Synthesis Reference

No information avaliable

Brompheniraminum [INN-Latin] Molecular Weight

319.24 g/mol

Brompheniraminum [INN-Latin] Melting Point

No information avaliable

Brompheniraminum [INN-Latin] H2O Solubility

No information avaliable

Brompheniraminum [INN-Latin] State

Solid

Brompheniraminum [INN-Latin] LogP

3.74

Brompheniraminum [INN-Latin] Dosage Forms

Tablet

Brompheniraminum [INN-Latin] Indication

For treatment and relief of symptoms of allergies, hay fever, and colds

Brompheniraminum [INN-Latin] Pharmacology

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Dexbrompheniramine is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Brompheniraminum [INN-Latin] Absorption

Antihistamines are well absorbed from the gastrointestinal tract after oral administration.

Brompheniraminum [INN-Latin] side effects and Toxicity

Signs of an overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.

Brompheniraminum [INN-Latin] Patient Information

Brompheniraminum [INN-Latin] Organisms Affected

Humans and other mammals